[Reactome-support] Automated Error Report

Justin Preece preecej at science.oregonstate.edu
Wed Nov 1 16:34:35 EDT 2017 

Fixed.

Neo4j was down...likely server outage on Sunday. Investigating...

- Justin

On 11/01/2017 10:32 AM, reactome-support at gramene.org wrote:
> Logback Log Messages
> ------------------------------------------------------------------------
>
> Log session start time Wed Nov 01 13:32:22 EDT 2017
>
> Date 	Thread 	Level 	Logger 	MDC 	Message
> 2017-11-01 12:13:20,133 	http-bio-8080-exec-105 	ERROR 	errorLogger 	
> 	An unspecified exception was caught for request: 
> http://localhost:8080/ContentService/data/pathways/low/entity/R-OSA-1114672 
>
> org.neo4j.ogm.drivers.http.request.HttpRequestException: 
> http://neo4j:react-app-user_pw@localhost:7474/db/data/transaction/commit: 
> Connect to localhost:7474 [localhost/127.0.0.1] failed: Connection 
> refused (Connection refused)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:228)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.executeRequest(HttpRequest.java:168)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:129)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:98)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:78)
>     at org.neo4j.ogm.session.Neo4jSession.query(Neo4jSession.java:368)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.query(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:69)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.neo4j.ogm.session.delegates.TransactionsDelegate.doInTransaction(TransactionsDelegate.java:58)
>     at 
> org.neo4j.ogm.session.Neo4jSession.doInTransaction(Neo4jSession.java:446)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.doInTransaction(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.mapToConcreteType(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.execute(QueryResultGraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.neo4j.repository.query.GraphRepositoryQuery.execute(GraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.doInvoke(RepositoryFactorySupport.java:482)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.invoke(RepositoryFactorySupport.java:460)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.data.projection.DefaultMethodInvokingMethodInterceptor.invoke(DefaultMethodInvokingMethodInterceptor.java:61)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor$1.proceedWithInvocation(TransactionInterceptor.java:99)
>     at 
> org.springframework.transaction.interceptor.TransactionAspectSupport.invokeWithinTransaction(TransactionAspectSupport.java:281)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor.invoke(TransactionInterceptor.java:96)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.dao.support.PersistenceExceptionTranslationInterceptor.invoke(PersistenceExceptionTranslationInterceptor.java:136)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.interceptor.ExposeInvocationInterceptor.invoke(ExposeInvocationInterceptor.java:92)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy242.getPathwaysForByStId(Unknown Source)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor_aroundBody2(PathwaysService.java:37)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor_aroundBody3$advice(PathwaysService.java:33)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor(PathwaysService.java:1)
>     at 
> org.reactome.server.service.controller.graph.PathwaysController.getPathwaysFor(PathwaysController.java:95)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.doInvoke(InvocableHandlerMethod.java:222)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.invokeForRequest(InvocableHandlerMethod.java:137)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.ServletInvocableHandlerMethod.invokeAndHandle(ServletInvocableHandlerMethod.java:110)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.invokeHandlerMethod(RequestMappingHandlerAdapter.java:814)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.handleInternal(RequestMappingHandlerAdapter.java:737)
>     at 
> org.springframework.web.servlet.mvc.method.AbstractHandlerMethodAdapter.handle(AbstractHandlerMethodAdapter.java:85)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:959)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:893)
>     at 
> org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:969)
>     at 
> org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:860)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:624)
>     at 
> org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:845)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:731)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:303)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:121)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.reactome.server.service.utils.CORSFilter.doFilterInternal(CORSFilter.java:28)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:220)
>     at 
> org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:122)
>     at 
> org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:505)
>     at 
> org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:170)
>     at 
> org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:103)
>     at 
> org.apache.catalina.valves.AccessLogValve.invoke(AccessLogValve.java:950)
>     at 
> org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:116)
>     at 
> org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:423)
>     at 
> org.apache.coyote.http11.AbstractHttp11Processor.process(AbstractHttp11Processor.java:1079)
>     at 
> org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:620)
>     at 
> org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:318)
>     at 
> java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1142)
>     at 
> java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:617)
>     at 
> org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
>     at java.lang.Thread.run(Thread.java:745)
> Caused by: org.apache.http.conn.HttpHostConnectException: Connect to 
> localhost:7474 [localhost/127.0.0.1] failed: Connection refused 
> (Connection refused)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:158)
>     at 
> org.apache.http.impl.conn.PoolingHttpClientConnectionManager.connect(PoolingHttpClientConnectionManager.java:353)
>     at 
> org.apache.http.impl.execchain.MainClientExec.establishRoute(MainClientExec.java:380)
>     at 
> org.apache.http.impl.execchain.MainClientExec.execute(MainClientExec.java:236)
>     at 
> org.apache.http.impl.execchain.ProtocolExec.execute(ProtocolExec.java:184)
>     at 
> org.apache.http.impl.execchain.RetryExec.execute(RetryExec.java:88)
>     at 
> org.apache.http.impl.execchain.RedirectExec.execute(RedirectExec.java:110)
>     at 
> org.apache.http.impl.client.InternalHttpClient.doExecute(InternalHttpClient.java:184)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:82)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:107)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:192)
>      ... 100 common frames omitted
> Caused by: java.net.ConnectException: Connection refused (Connection 
> refused)
>     at java.net.PlainSocketImpl.socketConnect(Native Method)
>     at 
> java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:350)
>     at 
> java.net.AbstractPlainSocketImpl.connectToAddress(AbstractPlainSocketImpl.java:206)
>     at 
> java.net.AbstractPlainSocketImpl.connect(AbstractPlainSocketImpl.java:188)
>     at java.net.SocksSocketImpl.connect(SocksSocketImpl.java:392)
>     at java.net.Socket.connect(Socket.java:589)
>     at 
> org.apache.http.conn.socket.PlainConnectionSocketFactory.connectSocket(PlainConnectionSocketFactory.java:74)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:141)
>      ... 110 common frames omitted
> 2017-11-01 12:13:38,385 	http-bio-8080-exec-100 	ERROR 	errorLogger 	
> 	An unspecified exception was caught for request: 
> http://localhost:8080/ContentService/data/pathways/low/entity/R-OSA-1114672 
>
> org.neo4j.ogm.drivers.http.request.HttpRequestException: 
> http://neo4j:react-app-user_pw@localhost:7474/db/data/transaction/commit: 
> Connect to localhost:7474 [localhost/127.0.0.1] failed: Connection 
> refused (Connection refused)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:228)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.executeRequest(HttpRequest.java:168)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:129)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:98)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:78)
>     at org.neo4j.ogm.session.Neo4jSession.query(Neo4jSession.java:368)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.query(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:69)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.neo4j.ogm.session.delegates.TransactionsDelegate.doInTransaction(TransactionsDelegate.java:58)
>     at 
> org.neo4j.ogm.session.Neo4jSession.doInTransaction(Neo4jSession.java:446)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.doInTransaction(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.mapToConcreteType(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.execute(QueryResultGraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.neo4j.repository.query.GraphRepositoryQuery.execute(GraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.doInvoke(RepositoryFactorySupport.java:482)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.invoke(RepositoryFactorySupport.java:460)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.data.projection.DefaultMethodInvokingMethodInterceptor.invoke(DefaultMethodInvokingMethodInterceptor.java:61)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor$1.proceedWithInvocation(TransactionInterceptor.java:99)
>     at 
> org.springframework.transaction.interceptor.TransactionAspectSupport.invokeWithinTransaction(TransactionAspectSupport.java:281)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor.invoke(TransactionInterceptor.java:96)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.dao.support.PersistenceExceptionTranslationInterceptor.invoke(PersistenceExceptionTranslationInterceptor.java:136)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.interceptor.ExposeInvocationInterceptor.invoke(ExposeInvocationInterceptor.java:92)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy242.getPathwaysForByStId(Unknown Source)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor_aroundBody2(PathwaysService.java:37)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor_aroundBody3$advice(PathwaysService.java:33)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor(PathwaysService.java:1)
>     at 
> org.reactome.server.service.controller.graph.PathwaysController.getPathwaysFor(PathwaysController.java:95)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.doInvoke(InvocableHandlerMethod.java:222)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.invokeForRequest(InvocableHandlerMethod.java:137)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.ServletInvocableHandlerMethod.invokeAndHandle(ServletInvocableHandlerMethod.java:110)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.invokeHandlerMethod(RequestMappingHandlerAdapter.java:814)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.handleInternal(RequestMappingHandlerAdapter.java:737)
>     at 
> org.springframework.web.servlet.mvc.method.AbstractHandlerMethodAdapter.handle(AbstractHandlerMethodAdapter.java:85)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:959)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:893)
>     at 
> org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:969)
>     at 
> org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:860)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:624)
>     at 
> org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:845)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:731)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:303)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:121)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.reactome.server.service.utils.CORSFilter.doFilterInternal(CORSFilter.java:28)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:220)
>     at 
> org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:122)
>     at 
> org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:505)
>     at 
> org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:170)
>     at 
> org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:103)
>     at 
> org.apache.catalina.valves.AccessLogValve.invoke(AccessLogValve.java:950)
>     at 
> org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:116)
>     at 
> org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:423)
>     at 
> org.apache.coyote.http11.AbstractHttp11Processor.process(AbstractHttp11Processor.java:1079)
>     at 
> org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:620)
>     at 
> org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:318)
>     at 
> java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1142)
>     at 
> java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:617)
>     at 
> org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
>     at java.lang.Thread.run(Thread.java:745)
> Caused by: org.apache.http.conn.HttpHostConnectException: Connect to 
> localhost:7474 [localhost/127.0.0.1] failed: Connection refused 
> (Connection refused)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:158)
>     at 
> org.apache.http.impl.conn.PoolingHttpClientConnectionManager.connect(PoolingHttpClientConnectionManager.java:353)
>     at 
> org.apache.http.impl.execchain.MainClientExec.establishRoute(MainClientExec.java:380)
>     at 
> org.apache.http.impl.execchain.MainClientExec.execute(MainClientExec.java:236)
>     at 
> org.apache.http.impl.execchain.ProtocolExec.execute(ProtocolExec.java:184)
>     at 
> org.apache.http.impl.execchain.RetryExec.execute(RetryExec.java:88)
>     at 
> org.apache.http.impl.execchain.RedirectExec.execute(RedirectExec.java:110)
>     at 
> org.apache.http.impl.client.InternalHttpClient.doExecute(InternalHttpClient.java:184)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:82)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:107)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:192)
>      ... 100 common frames omitted
> Caused by: java.net.ConnectException: Connection refused (Connection 
> refused)
>     at java.net.PlainSocketImpl.socketConnect(Native Method)
>     at 
> java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:350)
>     at 
> java.net.AbstractPlainSocketImpl.connectToAddress(AbstractPlainSocketImpl.java:206)
>     at 
> java.net.AbstractPlainSocketImpl.connect(AbstractPlainSocketImpl.java:188)
>     at java.net.SocksSocketImpl.connect(SocksSocketImpl.java:392)
>     at java.net.Socket.connect(Socket.java:589)
>     at 
> org.apache.http.conn.socket.PlainConnectionSocketFactory.connectSocket(PlainConnectionSocketFactory.java:74)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:141)
>      ... 110 common frames omitted
> 2017-11-01 12:13:49,050 	http-bio-8080-exec-93 	ERROR 	errorLogger 	
> 	An unspecified exception was caught for request: 
> http://localhost:8080/ContentService/data/pathways/low/entity/R-OSA-1114672/allForms 
>
> org.neo4j.ogm.drivers.http.request.HttpRequestException: 
> http://neo4j:react-app-user_pw@localhost:7474/db/data/transaction/commit: 
> Connect to localhost:7474 [localhost/127.0.0.1] failed: Connection 
> refused (Connection refused)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:228)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.executeRequest(HttpRequest.java:168)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:129)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:98)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:78)
>     at org.neo4j.ogm.session.Neo4jSession.query(Neo4jSession.java:368)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.query(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:69)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.neo4j.ogm.session.delegates.TransactionsDelegate.doInTransaction(TransactionsDelegate.java:58)
>     at 
> org.neo4j.ogm.session.Neo4jSession.doInTransaction(Neo4jSession.java:446)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.doInTransaction(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.mapToConcreteType(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.execute(QueryResultGraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.neo4j.repository.query.GraphRepositoryQuery.execute(GraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.doInvoke(RepositoryFactorySupport.java:482)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.invoke(RepositoryFactorySupport.java:460)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.data.projection.DefaultMethodInvokingMethodInterceptor.invoke(DefaultMethodInvokingMethodInterceptor.java:61)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor$1.proceedWithInvocation(TransactionInterceptor.java:99)
>     at 
> org.springframework.transaction.interceptor.TransactionAspectSupport.invokeWithinTransaction(TransactionAspectSupport.java:281)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor.invoke(TransactionInterceptor.java:96)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.dao.support.PersistenceExceptionTranslationInterceptor.invoke(PersistenceExceptionTranslationInterceptor.java:136)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.interceptor.ExposeInvocationInterceptor.invoke(ExposeInvocationInterceptor.java:92)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy242.getPathwaysForAllFormsOfByStId(Unknown 
> Source)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysForAllFormsOf_aroundBody4(PathwaysService.java:47)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysForAllFormsOf_aroundBody5$advice(PathwaysService.java:33)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysForAllFormsOf(PathwaysService.java:1)
>     at 
> org.reactome.server.service.controller.graph.PathwaysController.getPathwaysForAllFormsOf(PathwaysController.java:110)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.doInvoke(InvocableHandlerMethod.java:222)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.invokeForRequest(InvocableHandlerMethod.java:137)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.ServletInvocableHandlerMethod.invokeAndHandle(ServletInvocableHandlerMethod.java:110)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.invokeHandlerMethod(RequestMappingHandlerAdapter.java:814)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.handleInternal(RequestMappingHandlerAdapter.java:737)
>     at 
> org.springframework.web.servlet.mvc.method.AbstractHandlerMethodAdapter.handle(AbstractHandlerMethodAdapter.java:85)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:959)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:893)
>     at 
> org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:969)
>     at 
> org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:860)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:624)
>     at 
> org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:845)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:731)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:303)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:121)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.reactome.server.service.utils.CORSFilter.doFilterInternal(CORSFilter.java:28)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:220)
>     at 
> org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:122)
>     at 
> org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:505)
>     at 
> org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:170)
>     at 
> org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:103)
>     at 
> org.apache.catalina.valves.AccessLogValve.invoke(AccessLogValve.java:950)
>     at 
> org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:116)
>     at 
> org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:423)
>     at 
> org.apache.coyote.http11.AbstractHttp11Processor.process(AbstractHttp11Processor.java:1079)
>     at 
> org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:620)
>     at 
> org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:316)
>     at 
> java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1142)
>     at 
> java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:617)
>     at 
> org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
>     at java.lang.Thread.run(Thread.java:745)
> Caused by: org.apache.http.conn.HttpHostConnectException: Connect to 
> localhost:7474 [localhost/127.0.0.1] failed: Connection refused 
> (Connection refused)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:158)
>     at 
> org.apache.http.impl.conn.PoolingHttpClientConnectionManager.connect(PoolingHttpClientConnectionManager.java:353)
>     at 
> org.apache.http.impl.execchain.MainClientExec.establishRoute(MainClientExec.java:380)
>     at 
> org.apache.http.impl.execchain.MainClientExec.execute(MainClientExec.java:236)
>     at 
> org.apache.http.impl.execchain.ProtocolExec.execute(ProtocolExec.java:184)
>     at 
> org.apache.http.impl.execchain.RetryExec.execute(RetryExec.java:88)
>     at 
> org.apache.http.impl.execchain.RedirectExec.execute(RedirectExec.java:110)
>     at 
> org.apache.http.impl.client.InternalHttpClient.doExecute(InternalHttpClient.java:184)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:82)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:107)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:192)
>      ... 100 common frames omitted
> Caused by: java.net.ConnectException: Connection refused (Connection 
> refused)
>     at java.net.PlainSocketImpl.socketConnect(Native Method)
>     at 
> java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:350)
>     at 
> java.net.AbstractPlainSocketImpl.connectToAddress(AbstractPlainSocketImpl.java:206)
>     at 
> java.net.AbstractPlainSocketImpl.connect(AbstractPlainSocketImpl.java:188)
>     at java.net.SocksSocketImpl.connect(SocksSocketImpl.java:392)
>     at java.net.Socket.connect(Socket.java:589)
>     at 
> org.apache.http.conn.socket.PlainConnectionSocketFactory.connectSocket(PlainConnectionSocketFactory.java:74)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:141)
>      ... 110 common frames omitted
> 2017-11-01 12:13:53,281 	http-bio-8080-exec-107 	ERROR 	errorLogger 	
> 	An unspecified exception was caught for request: 
> http://localhost:8080/ContentService/data/pathways/low/entity/R-OSA-1114672 
>
> org.neo4j.ogm.drivers.http.request.HttpRequestException: 
> http://neo4j:react-app-user_pw@localhost:7474/db/data/transaction/commit: 
> Connect to localhost:7474 [localhost/127.0.0.1] failed: Connection 
> refused (Connection refused)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:228)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.executeRequest(HttpRequest.java:168)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:129)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:98)
>     at 
> org.neo4j.ogm.session.delegates.ExecuteQueriesDelegate.query(ExecuteQueriesDelegate.java:78)
>     at org.neo4j.ogm.session.Neo4jSession.query(Neo4jSession.java:368)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.query(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:69)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery$1.apply(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.neo4j.ogm.session.delegates.TransactionsDelegate.doInTransaction(TransactionsDelegate.java:58)
>     at 
> org.neo4j.ogm.session.Neo4jSession.doInTransaction(Neo4jSession.java:446)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.aop.support.AopUtils.invokeJoinpointUsingReflection(AopUtils.java:302)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.invokeJoinpoint(ReflectiveMethodInvocation.java:190)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:157)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.doProceed(DelegatingIntroductionInterceptor.java:133)
>     at 
> org.springframework.aop.support.DelegatingIntroductionInterceptor.invoke(DelegatingIntroductionInterceptor.java:121)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy218.doInTransaction(Unknown Source)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.mapToConcreteType(QueryResultGraphRepositoryQuery.java:64)
>     at 
> org.springframework.data.neo4j.repository.query.QueryResultGraphRepositoryQuery.execute(QueryResultGraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.neo4j.repository.query.GraphRepositoryQuery.execute(GraphRepositoryQuery.java:52)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.doInvoke(RepositoryFactorySupport.java:482)
>     at 
> org.springframework.data.repository.core.support.RepositoryFactorySupport$QueryExecutorMethodInterceptor.invoke(RepositoryFactorySupport.java:460)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.data.projection.DefaultMethodInvokingMethodInterceptor.invoke(DefaultMethodInvokingMethodInterceptor.java:61)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor$1.proceedWithInvocation(TransactionInterceptor.java:99)
>     at 
> org.springframework.transaction.interceptor.TransactionAspectSupport.invokeWithinTransaction(TransactionAspectSupport.java:281)
>     at 
> org.springframework.transaction.interceptor.TransactionInterceptor.invoke(TransactionInterceptor.java:96)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.dao.support.PersistenceExceptionTranslationInterceptor.invoke(PersistenceExceptionTranslationInterceptor.java:136)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.interceptor.ExposeInvocationInterceptor.invoke(ExposeInvocationInterceptor.java:92)
>     at 
> org.springframework.aop.framework.ReflectiveMethodInvocation.proceed(ReflectiveMethodInvocation.java:179)
>     at 
> org.springframework.aop.framework.JdkDynamicAopProxy.invoke(JdkDynamicAopProxy.java:208)
>     at com.sun.proxy.$Proxy242.getPathwaysForByStId(Unknown Source)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor_aroundBody2(PathwaysService.java:37)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor_aroundBody3$advice(PathwaysService.java:33)
>     at 
> org.reactome.server.graph.service.PathwaysService.getPathwaysFor(PathwaysService.java:1)
>     at 
> org.reactome.server.service.controller.graph.PathwaysController.getPathwaysFor(PathwaysController.java:95)
>     at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
>     at 
> sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
>     at 
> sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
>     at java.lang.reflect.Method.invoke(Method.java:498)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.doInvoke(InvocableHandlerMethod.java:222)
>     at 
> org.springframework.web.method.support.InvocableHandlerMethod.invokeForRequest(InvocableHandlerMethod.java:137)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.ServletInvocableHandlerMethod.invokeAndHandle(ServletInvocableHandlerMethod.java:110)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.invokeHandlerMethod(RequestMappingHandlerAdapter.java:814)
>     at 
> org.springframework.web.servlet.mvc.method.annotation.RequestMappingHandlerAdapter.handleInternal(RequestMappingHandlerAdapter.java:737)
>     at 
> org.springframework.web.servlet.mvc.method.AbstractHandlerMethodAdapter.handle(AbstractHandlerMethodAdapter.java:85)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:959)
>     at 
> org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:893)
>     at 
> org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:969)
>     at 
> org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:860)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:624)
>     at 
> org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:845)
>     at javax.servlet.http.HttpServlet.service(HttpServlet.java:731)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:303)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:121)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.reactome.server.service.utils.CORSFilter.doFilterInternal(CORSFilter.java:28)
>     at 
> org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
>     at 
> org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
>     at 
> org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:220)
>     at 
> org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:122)
>     at 
> org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:505)
>     at 
> org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:170)
>     at 
> org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:103)
>     at 
> org.apache.catalina.valves.AccessLogValve.invoke(AccessLogValve.java:950)
>     at 
> org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:116)
>     at 
> org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:423)
>     at 
> org.apache.coyote.http11.AbstractHttp11Processor.process(AbstractHttp11Processor.java:1079)
>     at 
> org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:620)
>     at 
> org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:316)
>     at 
> java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1142)
>     at 
> java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:617)
>     at 
> org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
>     at java.lang.Thread.run(Thread.java:745)
> Caused by: org.apache.http.conn.HttpHostConnectException: Connect to 
> localhost:7474 [localhost/127.0.0.1] failed: Connection refused 
> (Connection refused)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:158)
>     at 
> org.apache.http.impl.conn.PoolingHttpClientConnectionManager.connect(PoolingHttpClientConnectionManager.java:353)
>     at 
> org.apache.http.impl.execchain.MainClientExec.establishRoute(MainClientExec.java:380)
>     at 
> org.apache.http.impl.execchain.MainClientExec.execute(MainClientExec.java:236)
>     at 
> org.apache.http.impl.execchain.ProtocolExec.execute(ProtocolExec.java:184)
>     at 
> org.apache.http.impl.execchain.RetryExec.execute(RetryExec.java:88)
>     at 
> org.apache.http.impl.execchain.RedirectExec.execute(RedirectExec.java:110)
>     at 
> org.apache.http.impl.client.InternalHttpClient.doExecute(InternalHttpClient.java:184)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:82)
>     at 
> org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:107)
>     at 
> org.neo4j.ogm.drivers.http.request.HttpRequest.execute(HttpRequest.java:192)
>      ... 100 common frames omitted
> Caused by: java.net.ConnectException: Connection refused (Connection 
> refused)
>     at java.net.PlainSocketImpl.socketConnect(Native Method)
>     at 
> java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:350)
>     at 
> java.net.AbstractPlainSocketImpl.connectToAddress(AbstractPlainSocketImpl.java:206)
>     at 
> java.net.AbstractPlainSocketImpl.connect(AbstractPlainSocketImpl.java:188)
>     at java.net.SocksSocketImpl.connect(SocksSocketImpl.java:392)
>     at java.net.Socket.connect(Socket.java:589)
>     at 
> org.apache.http.conn.socket.PlainConnectionSocketFactory.connectSocket(PlainConnectionSocketFactory.java:74)
>     at 
> org.apache.http.impl.conn.DefaultHttpClientConnectionOperator.connect(DefaultHttpClientConnectionOperator.java:141)
>      ... 110 common frames omitted
>
>
>
> _______________________________________________
> Reactome-support mailing list
> Reactome-support at gramene.org
> http://brie4.cshl.edu/mailman/listinfo/reactome-support

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://brie4.cshl.edu/pipermail/reactome-support/attachments/20171101/709543c9/attachment-0001.html>

More information about the Reactome-support mailing list