Sorghum Genome Sequence announcement
Claire Hebbard
cer17 at cornell.edu
Wed Nov 29 08:58:44 EST 2006
To: Gramene List-serve
Here is a letter from Dr. Andrew Paterson concerning the Sorghum
Genome Sequence.
[begin letter]
20 Nov 2006
TO: Anyone interested in the sorghum genome sequence (please
circulate this as widely as possible).
As you may know, the US Department of Energy Joint Genome Institute,
under its 'Community Sequencing Program' has made rapid progress
toward its commitment to provide 8X sequence coverage of the genome
of Sorghum bicolor L. genotype, BTx623. These data will be combined
with publicly
available sequences, assembled into 'contigs' (contiguous sequences
without gaps) and 'scaffolds' (reconstructed stretches with any gaps
spanned by at least two end-sequenced clones), and integrated with
extensive physical and genetic maps to yield genetically-oriented
pseudomolecules that are anticipated to substantially cover most
sorghum chromosomes.
Sorghum sequence assemblies will be made available in advance of
publication, under the principles of the 'Ft Lauderdale' agreement
(http://72.14.209.104/search?q=cache:ag5ZX7CDIdkJ:www.wellcome.ac.uk/assets/wtd003207.pdf+Ft+Lauderdale+sequence&hl=en&gl=us&ct=clnk&cd=1)
to protect the interests of scientists who wish to share
pre-publication data with the community, i.e. with a request that
users defer publication of any whole-genome scale analyses until the
sequencing group has published its primary analysis. Leading
scientific journals are also being notified. A 4x assembly is now
available at https://www.jgi.doe.gov/downloads/Sorghum_bicolor. Use
Sorghum_bicolor and ^ico at hgr as login and password, respectively. We
anticipate that the genetically- oriented 8x assembly will be
available in early 2007, barring unexpected delays.
A team has been assembled to conduct initial annotation and analysis
of the sequence for publication in a leading refereed journal.
Although many dimensions of the planned analysis are covered,
inquiries about possible participation in this effort should be
directed to Dr Paterson (paterson at uga.edu). Team members are
responsible for providing their own funding to support their
participation.
Since the primary publication of the sequence will only be able to
succinctly describe a few key features, two leading journals have
offered to consider companion papers that address specific features
in detail, for coordinated publication shortly following the primary
sequence, in a 'special section' or perhaps 'special issue'.
1. Genome Research (www.genome.org/) has agreed to consider
large-scale genomic studies that present novel data of biological
significance.
2. The Plant Genome (www.crops.org/genome/) has agreed to consider
research that shows clear potential for translating genomic
technology into agronomic advancement.
Both journals will review sorghum genome-related submissions
according to their established mechanisms and standards. At an
appropriate time, the respective journals will provide further
details. We hope that this information is useful in planning for
engagement of these new genomic resources for
sorghum in your work. We also hope that you share our excitement
about these new resources, which promise to add new dimensions to our
understanding of botanical and genomic diversity, as well as new
opportunities for improvement of leading food, feed, forage & turf,
and biofuels crops. We encourage you to consider how the sorghum
sequence might fit into your research plans, to submit manuscripts to
the coordinated reviews as appropriate, and to contact us with any
questions.
Andrew H. Paterson
Lead Proposer, CSP Sorghum Sequencing Project
Chair, Sorghum Genomics Executive Committee
Daniel S. Rokhsar
Program Head for Computational Genomics
Joint Genome Institute
[end letter]
--
*******************************************
Claire Hebbard
Gramene Outreach Coordinator
G15 Bradfield Hall
Ithaca, NY 14853
www.gramene.org
ph: 607-255-4199
*******************************************
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