most informative genetic marker type

Susan McCouch srm4 at cornell.edu
Thu Nov 16 17:12:16 EST 2006


Dear Richard,

Yes, if you are working within a species and particularly if the  
strains you want to distinguish are closely related, microsatellite  
markers are probably the most informative markers to use.

If there are not alot of microsatellites available for your species,  
you can always use AFLP, but a majority of the bands will not be  
informative, you know nothing about allelic relationships among  
bands, and you have only "dominant / recessive" information to work  
with.

The microsatellites are co-dominant, have multiple alleles per locus  
and are usually already mapped, so you usually get more information  
per marker from them.

I hope this is helpful.

Regards,
Susan McCouch

On Aug 31, 2006, at 11:13 AM, richard hampson wrote:

>
> Dear Sir/Madam
>
> When comparing closely related strains of the same grass species,  
> is there any information as to which marker type is the most likely  
> to be informatice. Are microsatellites the best bet?
>
> Thanks for your help,
>
> Richard
> Richard Hampson PhD
>
> Oryzon Genomics
>
> Parc Científic de Barcelona
>
> Josep Samitier, 1-5
>
> 08028 Barcelona
>
> Spain
>
>
>
> phone: (34) 93 40 34 744
>
> fax: (34) 93 40 34 792
>
>
>
> www.oryzon.com
>
>
>
>
>
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