[Obo-cell-type] GO and Cell ontologies

Pankaj Jaiswal pj37 at cornell.edu
Wed Apr 20 10:59:53 EDT 2005


If you all agree, for plants perspective, my suggestion is that all the 
plant cell instances and their nomenclature be made consistent with the 
terms coming from Plant Ontology project. This will help us to create 
equivalences in a automated way if not manually.

Synergid
http://www.plantontology.org/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=PO:0000191&show_associations=terms
Egg cell
http://www.plantontology.org/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=PO:0020094&show_associations=terms

Pankaj


J Clark wrote:
> Hi Michael,
> 
> That all seems good to me.
> 
>  From the plant perspective I have checked a couple of text books and 
> the 'egg cell' is always referred to fully as the 'egg cell' not just 
> the 'egg'. The 'synergids' can be referred to as 'synergids' or 
> 'synergid cells' so 'synergid' would be fine.
> 
> Hope that helps,
> 
> Jen
> 
> 
> Michael Ashburner (Genetics) wrote:
> 
>> Both the GO and OBO CELL lists will have seen traffic recently concerning
>> the fact that GO and CL are out of synchrony with respect to the 
>> semantics
>> and relationships of cell types.  We must be committed to resolving 
>> these problems.
>> I see this as proceeding in several steps.
>>
>> Step 1. Address the semantic differences between GO and CL with respect
>> to cell types, and differences in synonomy.
>> These are the major subjects of this email and I thank Chris  & Mikel 
>> Aranguren for most of the examples.
>>
>> I would like comments on these proposed changes to both CL and GO, 
>> from Jonathan,
>> Sue Rhee and GO folk. Then, I and perhaps Jane will coordinate the 
>> changes
>> to the two ontologies.
>>
>> The next step will be to resolve differences in 
>> relationship/parenthood between
>> GO and CL and to resolve the proplems of 1 to many mappings from GO to 
>> CL.
>>
>> We will then need to bring the GO and CL definitions into synchrony.
>>
>> When we think we have done all of these, I guess the next will be for 
>> Chris
>> to re-run his scripts and see what we have missed.
>>
>> Then, I hope, we will be in a very good state for cross-product computes.
>>
>> Thankyou for your help - Michael
>> ======================================================================
>> Changes to CL:
>>
>> 1. REMOVE all _ and replaced by spaces.
>> 2. CORRECT spelling 'sperm cel' (synonym of CL:0000019).
>> 3. CHANGE default-namespace: to 'cell' from 'cell_ontology'.
>> 4. CHANGE all 'fat cell' to 'apidocyte' (with 'fat cell' as synonym) 
>> to bring in line with GO use.
>> 5. ADD parent 'cardioblast ; CL:NEW' for 'cardioblast (sensu Arthropoda)
>> 6. ADD as isa child of 'crystal cell':
>>     embryonic crystal cell
>>     lymph gland crystal cell
>> 7. ADD new cell type:
>>     heterocyst, isa 'prokaryotic cell'; isa 'nitrogen fixing cell ; 
>> CL:NEW'
>>         definition: A differentiated cell that functions as a site of
>>         nitrogen fixation under aerobic conditions.
>>     chlamydospore, isa a 'fungal cell'; isa 'asexual spore'
>>         definition: An asexual 1-celled spore (primarily for 
>> perennation, not dissemination) originating endogenously and singly 
>> within part of a pre-existing cell, by the contraction of the 
>> protoplast and possessing
>> an inner secondary and oftened thickened hyaline or brown wall, usually
>> impregnated with hydrophobic material. definition_reference: 
>> ISBN:085199377X
>> 8. ADD 'female gametophyte egg cell' as isa child of 'egg cell'
>> 9. CHANGE 'epithelial cell of trachea' to 'tracheal epithelial cell'
>> 10. ADD as develops_from 'granulosa_cell':
>>     cumulus cell ; CL:NEW
>>     stratum granulosum cell ; CL:NEW
>> with 'corona radiata cell ; CL:NEW' as being an isa cumulus cell
>> This all from Gray's page 123.
>> 11. ADD 'male gametophyte sperm cell ; CL:NEW' as isa of 'sperm cell 
>> (sensu Viridiplantae'
>> 12. [removed]
>> 13. CHANGE 'central cell' > 'female gametophyte central cell' (plant 
>> cell)
>> 14. ADD 'NT cell' as synonym of 'natural killer cell'
>> 15. ADD 'fusimotor neuron'
>>     is_a 'motor neuron'
>>     def: A subset of motor neurons that innervates intrafusal muscle 
>> fibers     and has small diameter axons.  PMID:15582775
>> 16. MAKE 'osteoclast' and 'macrophage'  both is_a's of 'monocyte'
>> 17. ADD 'eye photoreceptor cell ; CL:NEW' as isa 'photoreceptor cell'
>> 18. ADD 'retinal cone cell ; CL:NEW' as isa 'cone cell'
>> 19. MAKE 'trichome' also an isa of 'hair cell'
>> 20. CHANGE: 'blood platelet' > 'platlet' [I presume there is no other 
>> type of platlet ?]
>> 21. GO uses 'sperm', CL used 'spermatozoan'. I suggest CL changes the 
>> primary term
>> to 'sperm'
>> 22. GO uses 'striated muscle cell'; CL has only 'obliquely striated 
>> muscle cell'. Is there any other type of striated muscle cell ? If so 
>> CL should change.
>> =========================================================================
>> Need to decide with GO:
>>
>> 0. B cell vs B-cell vs B lymphocyte
>>    T cell vs T-cell vs T lymphocyte
>>    T-helper vs helper T' etc
>>    natural killer vs NK etc
>>
>> =========================================================================
>> Problems to be discussed with GO:
>>
>> 1. GO has the term 'thymocyte differentiation' defined as:           
>> '* Processes by which a relatively unspecialized hemopoietic stem cell 
>> acquires the specialized features of a thymocyte, a lymphocyte found 
>> in the thymus.'
>>
>> How does this fit into CL ?
>>
>> 2. [removed]
>> 3. I suggest all GO instances of 'mesoderm cell' be changed to
>> 'mesodermal cell' [similarly ectoderm, endoderm cell, if such exist in 
>> GO]
>>
>> 4. GO to change 'tracheal cell *' to 'tracheal epithelial cell *'
>> 5. GO to change 'ovarian cumulus cell differentiation' to 'cumulus 
>> cell differentiation'
>> 6. GO to change 'auditory hair cell' to 'auditory receptor cell'
>> 7. GO to change 'branch cell fate determination (sensu Insecta) -> 
>> branched_duct_epithelial_cell fate determination (sensu Insecta)'
>> 8. Is the GO usage of 'hemocyte' arthropod specific ? In this case
>> GO needs to change 'hemocyte differentiation (sensu Arthropoda)' by 
>> removing
>> the sensu.
>> 9. GO should add neuroblast_(sensu_Nematoda_and_Protostomia), 
>> neuroblast_(sensu_Vertebrata) as childs of neuroblast [cell] * terms
>> 10. GO should add erythrocyte_(sensu_Mammalia), 
>> erythrocyte_(sensu_non-Mammalia) as
>> childs of of erythrocyte * terms
>> 11. Does GO need epidermal_cell_(sensu_Insecta) * as childs of 
>> epidermal cell * terms ?
>> 12. ditto glial cell (sensu Nematoda and Protostomia) as childs of 
>> glial cell * terms ?
>> 13. ditto pigment cell (sensu Nematoda and Protostomia), pigment cell 
>> (sensu Vertebrata) as childs of pigment cell * terms ?
>> 14. The following terms in GO have 'cell' as a suffix. This suffix 
>> should be removed
>> from all terms:
>>     basophil cell
>>     egg cell
>>     hemocyte cell
>>     neuroblast cell
>>     neuron cell
>>     oocyte cell
>>     spermatid cell
>>     spermatocyte cell
>>     synergid cell
>>     trichome cell
>> 15. CL uses 'photoreceptor cell'; GO uses 'photoreceptor'. Are these 
>> the same?
>> We need to normalize. Suggestions ? Same is true of GO's 
>> 'mechanoreceptor' and CL's
>> 'mechanoreceptor cell'. CL should probably
>> add R1..R8 as isa of 'eye photoreceptor cell'
>> 16. GO has 'cone cell' and 'retinal cone cell' ... are these different 
>> ? i.e.
>> are their any non-retinal cone cells ? CL just has 'retinal cone cell'
>> 17. GO has both 'glia cell' and 'glial cell'. Change all former to 
>> 'glial cell'
>> 18. GO has 'border cell', CL has 'border follicle cell'. I suggest GO 
>> uses
>> the latter term.
>> 19. [removed]
>> 20. GO has 'cardioblast', CL 'cardioblast (sensu Arthropoda)'. Are all
>> cardioblasts Arthropod, which case CL can change and drop the sensu. 
>> If not
>> then GO needs to change.
>> 21. Go has both 'leukocyte cell' and 'leukocyte'. I suggest we change all
>> former to latter.
>> 22. GO has both 'mesoderm cell' & 'mesodermal cell'.  I suggest we 
>> change all
>> former to latter.
>> 23. GO should change all 'neuronal cell' to 'neuron'
>> 24. GO has 'spermatogonial cell', CL has 'spermatogonium'. I suggest 
>> GO changes to latter
>> =========================================================================== 
>>
>> These are NOT problems [this list mainly for Chris]:
>>
>> rhabdomere development .. The reason being is that 'rhabdomere' is 
>> part_of a photoreceptor cell
>> missing              seed ... not a cell
>> missing              sex ... not a cell
>> synonym              stalk cell .. I think GO & CL are consistent
>> synonym              pigment cell .. I think GO & CL are consistent
>> synonym              nurse cell .. I think GO & CL are consistent
>> synonym              muscle cell .. I think GO & CL are consistent
>> missing              cell homeostatic ... not a cell
>> missing              cell mass cell ... eh ?
>> missing              positive ... eh ?
>> missing              host cell ... not a cell type
>> missing              epidermal cell ... GO & CL consistent
>> missing              endothelial cell ... GO & CL consistent
>> missing              epithelial cell ... GO & CL consistent
>> missing              crest cell .. no GO has only 'neural crest cell' 
>> consistent with CL
>> missing              heterophilic cell ... not a cell type
>> missing              homophilic cell ... not a cell type
>> missing              inductive cell ... not a cell type
>> missing              kinase C ... not a cell type
>> missing              antipodal cell ... GO & CL consistent
>> missing              central cell ... GO & CL consistent
>> missing              crystal cell ... GO & CL consistent
>> missing              dendritic cell ... GO & CL consistent
>> missing              female gamete ... GO & CL consistent
>> missing              female sex ... eh ?
>> missing              female germ cell ... GO & CL consistent
>> missing              follicle cell ... GO & CL consistent
>> missing              garland cell ... GO & CL consistent
>> missing              germ cell ... GO & CL consistent
>> missing              guard cell ... GO & CL consistent
>> missing              guard mother cell ... GO & CL consistent
>> missing              hyphal cell ... GO & CL consistent
>> missing              male gamete ... GO & CL consistent
>> missing              male germ cell ... GO & CL consistent
>> missing              male sex ... not a cell
>> missing              mast cell... GO & CL consistent
>> missing              microglial cell... GO & CL consistent
>> missing              mother cell .. not in GO, though 'guard mother' 
>> and 'ganglion mother' are and are consistent with CL
>> missing              phospholipase C ... not a cell
>> missing              ocellus ... not a cell
>> missing              neural crest cell ... GO & CL consistent
>> missing              pericardial cell ... GO & CL consistent
>> missing              pole cell ... GO & CL consistent
>> missing              protein kinase C ... not a cell
>> missing              retinal cone cell ... GO & CL consistent
>> missing              smooth muscle cell ... GO & CL consistent
>> missing              spermatid nuclear ... eh ? .. spermatid is in CL
>> missing              stem cell ... GO & CL consistent
>> missing              tryptophan hydroxylase ... not a cell
>>
>>
>> =========================================================================== 
>>
>> These cells are already in CL:
>>
>> natural killer cell differentiation (CL:0000623)
>> =========================================================================== 
>>
>>
>> GO has these cell types not in CL - ideas on what
>> to do ?. I have grouped the immunology terms at top. There may be some
>> redundancy with what is above.
>>
>>
>> missing              B-1 B-cell
>> missing              NK T-cell
>> missing              T-helper 1 cell
>> missing              T-helper 2 cell
>> missing              T-helper cell
>> missing              activated T-cell
>> missing              alpha-beta T-cell
>> missing              extrathymic T-cell
>> missing              helper cell
>> missing              cytotoxic T-cell
>> missing              gamma-delta T-cell
>> missing              immune cell
>> missing              killer cell
>> missing              myeloid blood cell
>> missing              natural killer cell
>> missing              negative extrathymic T-cell
>> missing              negative thymic T-cell
>> missing              positive extrathymic T-cell
>> missing              positive thymic T-cell
>> missing              thymic T-cell
>> missing              thymocyte
>> missing              regulatory T-cell
>>
>> missing              abaxial cell
>> missing              ameboid cell
>> missing              anterior cone cell
>> missing              aortic cell (sensu Insecta)
>> missing              autophagic cell
>> missing              axial mesoderm cell
>> missing              azurophil
>> missing              blood cell
>> missing              cardiac cell
>> missing              cystoblast cell
>> missing              early stripe melanocyte
>> missing              edge cell
>> missing              embryonic crystal cell
>> missing              embryonic hemocyte
>> missing              embryonic plasmatocyte
>> missing              equatorial cone cell
>> missing              eye photoreceptor cell
>> missing              gametophyte central cell
>> missing              gametophyte egg cell
>> missing              gametophyte sperm cell
>> missing              gland cell
>> missing              gland crystal cell
>> missing              gland hemocyte
>> missing              gland plasmatocyte
>> missing              heart proper cell
>> missing              inner cell mass cell
>> missing              intermediate mesoderm cell
>> missing              iridophore
>> missing              larval midgut cell
>> missing              late stripe melanocyte
>> missing              lateral mesoderm cell
>> missing              leading edge cell
>> missing              leukocyte
>> missing              lymph gland crystal cell
>> missing              lymph gland hemocyte
>> missing              lymph gland plasmatocyte
>> missing              male gametophyte sperm cell
>> missing              mass cell
>> missing              midgut cell
>> missing              mystery cell fate
>> missing              non-eye photoreceptor cell
>> missing              organ precursor cell
>> missing              paraxial mesoderm cell
>> missing              polar cone cell
>> missing              polarized epithelial cell
>> missing              pollen
>> missing              pollen germ cell
>> missing              posterior cone cell
>> missing              precursor cell
>> missing              primary cell
>> missing              primary endosperm
>> missing              primary pigment cell
>> missing              retinal cell
>> missing              root epidermal cell
>> missing              salivary gland cell
>> missing              secondary cell
>> missing              secondary pigment cell
>> missing              sensory organ precursor cell
>> missing              somatic stem cell
>> missing              stripe melanocyte
>> missing              tertiary pigment cell
>> missing              tracheal cell
>> missing              trophectoderm cell
>> missing              urothelial cell
>>
>>
>>
>>
>>
>>
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> 
> 

-- 
************************
Pankaj Jaiswal, PhD
G15-Bradfield Hall
Dept. of Plant Breeding
Cornell University
Ithaca, NY-14853, USA

Tel: +1-607-255-3103
      +1-607-255-4109
Fax: +1-607-255-6683
http://www.gramene.org
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