[Gmod-help] Phylogenetic display in Gbrowse
Mark Ok
mokada23 at hotmail.com
Mon Dec 24 16:45:43 EST 2007
Hi all,
My name is Mark and I am the student that worked on a Phylogenetic track during the summer with Lincoln Stein. I will summarise what I have implemented and plan to do in the next while.
The idea of the track is to display an alignment of multiple species alongside a simple cladogram. When zoomed in, a DNA alignment is drawn and when zoomed out, a log-scale histogram of the alignment scores are drawn across the species.
+-------------------------- the track ----------------------+|+====================== the cladeogram glyph==============+||| ||||+--------------alignment glyph 1------------+ ---| |||| |--|---cladeogram||+--------------alignment glyph 2------------+ ---| | ||||+--------------alignment glyph 3------------+ ------+ ||| +=========================================================+|+-------------------------- the track ----------------------+
The track makes use of:
-Gap details from the GFF3 format attribute (as explained in http://www.sequenceontology.org/gff3.shtml).
-Cladogram data from a tree file readable with Bio::TreeIO
A simple example is explained in an edited version of the tutorial at:
gbrowse/tutorial/tutorial.phyTreeEdit.html
of the head version.
Right now I am in attempting to incorporate Lincoln's libraries which will allow Wiggle and Dense files to be drawn for the alignment scores.
This track is still a work in progress and I apologise for my slow pace since the summer. I am also a beginner at programming gbrowse as well as in phylogenetics in general and would appreciate any feedback.
thank you very much,
Hisanaga Mark Okada
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